Foxm1 in cancer
WebMar 5, 2013 · FoxM1 has been reported to modulate drug sensitivity and resistance in various tumor types. In breast cancer cell lines with acquired resistance for cisplatin or epirubicin FoxM1 was found to be overexpressed and its depletion was able to re-sensitize these cell lines to the respective genotoxic drug ( Kwok et al., 2010; Monteiro et al., 2012 ). WebApr 10, 2024 · Accumulating evidence has implicated a pivotal role for FOXO3, FOXM1 and SIRT6 in cancer progression. The majority of researches focused on the functions of these proteins in drug resistance, but their relationships with radiotherapy (RT) response remain unclear. In this study, we examined protein expression of FOXO3, FOXM1 and SIRT6 …
Foxm1 in cancer
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WebOverexpression of FOXM1 has been reported in more than 20 types of human cancer. In recent years, FOXM1 has been implicated in diverse cellular processes and also a … WebJun 8, 2011 · Consistent with this notion, FOXM1 has been found to be frequently upregulated in a host of human cancers, including colorectal ( 23 ), lung ( 24 ), prostate ( 25 ), liver ( 26 ), stomach ( 38 ), breast ( 27 ), and basal cell carcinomas ( 39) as well as glioblastoma ( 40 ).
WebJun 11, 2024 · The FOXM1 signaling pathway underlying the ERRγ-mediated gastric cancer suppression was identified. Furthermore, combined treatment with EZH2 inhibitor and ERRγ agonist synergistically suppressed GC progression by inhibiting this signaling pathway, suggesting its high potential in treating GC patients. Introduction WebJul 11, 2024 · In the current study, we found that DNMT1-mediated FOXO3a promoter hypermethylation leads to downregulation of FOXO3a expression in breast cancer, and FOXO3a suppresses BCSC properties and...
WebJun 14, 2024 · FOXM1A is a transcriptional repressor that locates in cytoplasm. FOXM1C is a transcriptional activator overexpressed in some tumors, and FOXM1D predominantly … WebCircRNA ZNF609 Knockdown Represses the Development of Non-Small Cell Lung Cancer via miR-623/FOXM1 Axis Javascript is currently disabled in your browser. Several features of this site will not function whilst javascript is disabled.
WebOur meta-analysis included nine studies and 1,686 patients, suggesting that overexpression of FoxM1 predicted a poor 3-year, 5-year overall survival. Moreover, the results also …
WebMay 1, 2024 · FOXM1 promoted the tumorigenesis of CRC in vitro To explore the effects of FOXM1 on CRC progression in vitro, we obtained FOXM1 upregulating and downregulating cells for our subsequent experiments in vitro. business donationsWebSep 12, 2024 · Regulation of the master regulator FOXM1 in cancer Abstract. FOXM1 (forkhead box protein M1) is a critical proliferation … business doncaster grantsWebNov 1, 2024 · FOXM1 is a master regulator of cell cycle function. The dysregulated expression of FOXM1 has been linked with tumorigenesis of many human malignancies ( … business done online clueWebExpression and functional characterization of FOXM1 in non-small cell lung cancer Yan Zhang, Wen-bin Qiao, Li Shan Department of Thoracic Oncology, Tumor Hospital Affiliated to Xinjiang Medical University, Xinjiang, People’s Republic of China Objectives: FOXM1 is a key member of the FOX transcription factor family, which plays a vital role in a series of … business doncaster business supportWebMar 7, 2014 · FOXM1 is a transcription factor that transactivates AURKA and other G2/M genes like PLK1, CDK1, and CCNB1 (16) (17) (18). High FOXM1 expression was reported in many cancers including oral... business doncaster logoWebGiven that FOXM1 is known to be involved in endocrine resistance, expansion of stem-like cancer cells, stem cell self-renew, cancer initiation and metastasis, it is conceivable that … business donation tax deductionWebDec 1, 2024 · FOXM1 is a master regulator in cancer 25 and promotes cancer progression through many pathways including key roles in tumor proliferation, cell cycle progression, DNA damage repair, angiogenesis ... business done online crossword