Introns are found in the genes of most organisms and many viruses and they can be located in both protein-coding genes and genes that function as RNA (noncoding genes). There are four main types of introns: tRNA introns, group I introns, group II introns, and spliceosomal introns (see below). Zobacz więcej An intron is any nucleotide sequence within a gene that is not expressed or operative in the final RNA product. The word intron is derived from the term intragenic region, i.e. a region inside a gene. The term intron refers to both … Zobacz więcej Introns were first discovered in protein-coding genes of adenovirus, and were subsequently identified in genes encoding transfer RNA … Zobacz więcej Splicing of all intron-containing RNA molecules is superficially similar, as described above. However, different types of introns were identified through the examination of intron structure by DNA sequence analysis, together with genetic and … Zobacz więcej Introns may be lost or gained over evolutionary time, as shown by many comparative studies of orthologous genes. Subsequent analyses have identified thousands of examples of intron loss and gain events, and it has been proposed that the emergence … Zobacz więcej The frequency of introns within different genomes is observed to vary widely across the spectrum of biological organisms. For … Zobacz więcej The spliceosome is a very complex structure containing up to one hundred proteins and five different RNAs. The substrate of … Zobacz więcej While introns do not encode protein products, they are integral to gene expression regulation. Some introns themselves encode functional RNAs through further processing after splicing to generate noncoding RNA molecules. Alternative splicing Zobacz więcej WitrynaSelfish DNA and the origin of introns. Selfish DNA and the origin of introns. Selfish DNA and the origin of introns Nature. 1985 May;315(6017):283-4. doi: 10.1038/315283b0. Author T Cavalier-Smith. PMID: 2987701 DOI: 10.1038/315283b0 No abstract available. Publication types ...
Intron - an overview ScienceDirect Topics
Witryna14 sie 2006 · The likely ancestors of spliceosomal introns are the group II self-splicing introns whose terminal structures, which form the splicing ribozyme, show remarkable … Witryna1 sie 2008 · The origin of spliceosomal introns is one of molecular biology's longest standing mysteries. Very few cases of intron ‘birth’ have been thoroughly … helix alm floating license
Introns and the origin of nucleus–cytosol compartmentalization
Witryna10 kwi 2014 · Qu et al. provide new grist for the introns origin mill (), adding one more chapter to what has become a very long narrative.Back in the day when spliceosomal introns in the protein-coding genes of eukaryotes were still very new to science (1977–1978), some of us argued that—in an evolutionary sense—they were actually … Witryna14 sie 2006 · Firstly, there is growing evidence that spliceosomal introns evolved from group II self-splicing introns which are present, usually, in small numbers, in many … Witryna2 cze 2014 · Origin of spliceosomal introns and alternative splicing In this work we review the current knowledge on the prehistory, origins, and evolution of spliceosomal … helix alm